Properties
Description
ONX-0914, soluble in DMSO and ethanol and insoluble in water, interferes with the proteasome’s ability to degrade proteins, thereby disrupting cellular processes in cancer cells, particularly multiple myeloma. It targets LMP7.
Molecular Formula
C31H40N4O7
Solubility
DMSO: 87 mg/mL (149.82 mM); Water: Insoluble; Ethanol: 87 mg/mL (149.82 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
ONX-0914 selectively inhibits specific proteasome subunits, with therapeutic implications in autoimmune diseases.
