Protein Serine/Threonine phosphatase inhibitor Ascomycin, Purity ≥98%

Synonym: 104987-12-4; FK 520; FR 900520; FK520; FR900520; Protein serine/threonine ohosphatase inhibitor

CAS Number: 104987-12-4
Compound CID: 5282071

Product Size

10 mg; 25 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Ascomycin, soluble in DMSO and ethanol and insoluble in water, inhibits enzymes that dephosphorylate serine and threonine residues in proteins, affecting various cellular signaling processes. It targets Calcineurin phosphatase.

Molecular Weight

792.01

Molecular Formula

C₄₃H₆₉NO₁₂

Targets

Calcineurin phosphatase: 49 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 98 mg/mL (123.73 mM); Water: Insoluble; Ethanol: 98 mg/mL (123.73 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

Ascomycin can be used to study immunosuppressive mechanisms by inhibiting calcineurin.