Cat. No.: X24-05-ZQ332
Protein Serine/Threonine phosphatase inhibitor Cyclosporine, Purity ≥98%
Synonym: 79217-60-0; Cyclosporine; Restasis; SangCyA; 30-Ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone; Protein serine/threonine ohosphatase inhibitor
- CAS Number: 79217-60-0
- Compound CID: 6435893
Product Size
100 mg; 250 mg; 500 mg; 1000 mg
Properties
Description
Cyclosporine, soluble in warmed DMSO and ethanol and insoluble in water, inhibits enzymes that dephosphorylate serine and threonine residues in proteins, affecting various cellular signaling processes. It targets Calcineurin phosphatase.
Molecular Weight
1,202.61
Molecular Formula
C62H111N11O12
Targets
Calcineurin phosphatase
Solubility
Warmed DMSO: 85 mg/mL (70.68 mM); Water: Insoluble; Ethanol: 85 mg/mL (70.68 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Cyclosporine is widely used to explore immunosuppressive mechanisms and T-cell function by inhibiting calcineurin.
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