PRX-08066

Synonym: 866206-54-4; 5-((4-(6-Chlorothieno(2,3-d)pyrimidine-4-ylamino)piperidin-1-yl)methyl)-2-fluorobenzonitrile

CAS Number: 866206-54-4
Compound CID: 11502243

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PRX-08066, soluble in DMSO, ethanol and water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT2B receptor.

Molecular Weight

401.89

Molecular Formula

C₁₉H₁₇ClFN₅S

Targets

5-HT2B receptor: 3.4 nM

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 92 mg/mL (177.61 mM); Water: 92 mg/mL (177.61 mM); Ethanol: 86 mg/mL (166.03 mM)

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

PRX-08066 can be used for its ability to inhibit the proliferation of smooth muscle cells in the pulmonary arteries and improve pulmonary hemodynamics.

Storage

Store at -20°C, and keep desiccated.