Structure of Psl Polysaccharide from Pseudomonas aeruginosa

The Psl polysaccharide is made up of five sugar residues that are bonded together in a linear polysaccharide chain. The interaction of Psl polysaccharide with an isoprenoid lipid carrier improves its structural integrity, which is important in the generation and assembly of Psl polysaccharides within the P. aeruginosa cell membrane. Extensive research using techniques such as nuclear magnetic resonance spectroscopy, X-ray crystallography, and mass spectrometry has revealed extensive insights into the structure of Psl polysaccharide and its relevance in the P. aeruginosa life cycle. This research has shed light on the Psl polysaccharide's molecular architecture and characteristics, adding to a better knowledge of its activities and prospective uses in numerous biological processes.

Fig.1 Structures of alginate and Psl polysaccharide. (Franklin, et al., 2011)

P. aeruginosa Psl Polysaccharide Production Service at CD BioGlyco

CD BioGlyco works in the biosynthesis of Psl polysaccharides in P. aeruginosa, offering comprehensive services tailored to our client's requirements. Our services encompass bacteria culture, Psl extraction, and purification, all executed with a commitment to delivering high-quality Psl polysaccharides. For a visual representation of our typical production process, please refer to the illustrative diagram provided below (Fig.2). In addition to our Psl polysaccharide services, CD BioGlyco provides a diverse range of P. aeruginosa Polysaccharide Antigen Production Services, catering to the unique needs of our clients. We take great pride in our one-stop Carbohydrate-based Vaccine Development Platform, which provides a comprehensive solution for vaccine development. Count on CD BioGlyco for dependable and efficient services, supported by our expertise and unwavering dedication to quality. We are fully committed to supporting your research and development endeavors in the fields of polysaccharides and vaccine development.

Fig.2 Standard production of microbial polysaccharide. (CD BioGlyco)

Advantages of Us

• We provide the one-stop Psl polysaccharide production service for clients, from extraction and purification to characteristics and quality control.
• Our talented scientists and well-experienced laboratory team have the ability to perform our analytical experiments and subsequent data analysis in good quality, providing our clients with reliable laboratory reports.
• Our service team is available to respond to inquiries from clients around the world promptly.

CD BioGlyco establishes a high-quality production platform, and we have the ability to offer custom Polysaccharide Antigen Production Services. If you have any questions or require detailed information, please feel free to contact us.

Reference:

1. Franklin, M.J.; et al. Biosynthesis of the Pseudomonas aeruginosa extracellular polysaccharides, alginate, Pel, and PSL. Frontiers in Microbiology. 2011, 2.