PTP inhibitor Ertiprotafib, Purity ≥98%

Synonym: 251303-04-5; PTP 112; PTP112; PTP-112; Protein tyrosine phosphatase inhibitor

CAS Number: 251303-04-5
Compound CID: 157049

Product Size

1 mg; 5 mg; 10 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Ertiprotafib blocks the activity of enzymes that remove phosphate groups from tyrosine residues in proteins, affecting signal transduction and cellular processes. It targets IKK-β, PPARα, PPARβ, and PTP1B.

Molecular Weight

559.51

Molecular Formula

C₃₁H₂₇BrO₃S

Targets

IKK-β: 400 nM; PPARα: 1 μM (EC₅₀); PPARβ: 1 μM (EC₅₀); PTP1B: 1.6 μM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

Ertiprotafib can be used to investigate the inhibition of protein tyrosine phosphatase 1B (PTP1B) in metabolic disorder studies.