Properties
Description
Ertiprotafib blocks the activity of enzymes that remove phosphate groups from tyrosine residues in proteins, affecting signal transduction and cellular processes. It targets IKK-β, PPARα, PPARβ, and PTP1B.
Molecular Formula
C31H27BrO3S
Targets
IKK-β: 400 nM; PPARα: 1 μM (EC50); PPARβ: 1 μM (EC50); PTP1B: 1.6 μM
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Ertiprotafib can be used to investigate the inhibition of protein tyrosine phosphatase 1B (PTP1B) in metabolic disorder studies.
