PTP inhibitor NSC87877 disodium salt, Purity ≥98%

Synonym: 56932-43-5; NSC-87877; NSC 87877; Protein tyrosine phosphatase inhibitor

CAS Number: 56932-43-5
Compound CID: 92576

Product Size

10 mg; 25 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

NSC87877 disodium salt, soluble in DMSO and water and insoluble in ethanol, blocks the activity of enzymes that remove phosphate groups from tyrosine residues in proteins, affecting signal transduction and cellular processes. It targets SHP-1 and SHP-2.

Molecular Weight

503.42

Molecular Formula

C₁₉H₁₃N₃O₇S₂.2Na

Targets

SHP-1: 355 nM; SHP-2: 318 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 85 mg/mL (168.84 mM); Water: 85 mg/mL (168.84 mM); Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

NSC87877 disodium salt can be used to inhibit SHP2 and SHP1 phosphatase activities in various cellular signaling studies.