Properties
Description
rac-Rotigotine Hydrochloride inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT1A receptor, 5-HT2B receptor, alpha-2B adrenergic receptor, D1 receptor, D2 receptor, D3 receptor, D4 receptor, and D5 receptor.
Molecular Formula
C19H26ClNOS
Targets
5-HT1A receptor: 30 nM; 5-HT2B receptor: 27 nM; Alpha-2B adrenergic receptor; D1 receptor: 83 nM; D2 receptor: 13.5 nM; D3 receptor: 0.71 nM; D4 receptor: 3.9-15 nM; D5 receptor: 5.4 nM
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
rac-Rotigotine hydrochloride can be used for research on Parkinson's disease and restless legs syndrome.
Storage
Store at -20°C, and keep desiccated.
