Properties
Description
RAD51 inhibitor B02, soluble in warmed DMSO and warmed ethanol and insoluble in water, disrupts homologous recombination and DNA repair by targeting the RAD51 protein, enhancing the cytotoxic effects of DNA-damaging agents in cancer therapy.
Molecular Formula
C22H17N3O
Solubility
Warmed DMSO: 66 mg/mL (194.46 mM); Water: Insoluble; Warmed ethanol: 20 mg/mL (58.92 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
RAD51 inhibitor B02 can be used to block RAD51 activity and study homologous recombination in DNA repair.