RAD51 inhibitor RI-1, Purity ≥98%

Synonym: 415713-60-9; RI-1; 3-Chloro-1-(3,4-dichlorophenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione; 3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione; RAD51 inhibitor

CAS Number: 415713-60-9
Compound CID: 1074953

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

RI-1, soluble in DMSO and insoluble in ethanol and water, disrupts homologous recombination and DNA repair by targeting the RAD51 protein, enhancing the cytotoxic effects of DNA-damaging agents in cancer therapy. It targets RAD51.

Molecular Weight

361.61

Molecular Formula

C₁₄H₁₁Cl₃N₂O₃

Targets

RAD51: <30 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 48 mg/mL (132.74 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

RI-1 can be used to inhibit RAD51 and investigate DNA repair pathways.

Storage

Store at -20ºC.