Raf inhibitor AZ304, Purity ≥98%

Synonym: 942507-42-8; AZ304; 3-(2-Cyanopropan-2-yl)-N-(3-((7-methoxyquinazolin-4-yl)amino)-4-methylphenyl)benzamide; 3-(2-Cyanopropan-2-yl)-N-[3-[(7-methoxyquinazolin-4-yl)amino]-4-methylphenyl]benzamide; Raf inhibitor

MDL: MFCD31812677
CAS Number: 942507-42-8
Compound CID: 16202218

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AZ304, soluble in DMSO and ethanol and insoluble in water, blocks a MAPK/ERK signaling pathway. It targets BRAF V600E, BRAFWT, CRAF, and CSF1R.

Molecular Weight

451.53

Molecular Formula

C₂₇H₂₅N₅O₂

Targets

BRAF V600E: 38 nM; BRAFWT: 79 nM; CRAF: 68 nM; CSF1R: 35 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 81 mg/mL (179.39 mM); Water: Insoluble; Ethanol: 5 mg/mL (11.07 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

AZ304 can be used to study its selective inhibition of mutant BRAF in various cancer models.

Storage

Store at -20ºC.