Raf inhibitor B-Raf IN 1, Purity ≥98%

Synonym: B-Raf IN 1; 950736-05-7; N-[3-(3-{4-[(dimethylamino)methyl]phenyl}pyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide; B-Raf-IN-1; MDK36057; CHEMBL1087397; N-[3-[3-[4-[(dimethylamino)methyl]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide; Raf inhibitor

MDL: MFCD25977055
CAS Number: 950736-05-7
Compound CID: 24884503

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

B-Raf IN 1, soluble in DMSO and ethanol and insoluble in water, blocks a MAPK/ERK signaling pathway. It targets B-Raf.

Molecular Weight

515.53

Molecular Formula

C₂₉H₂₄F₃N₅O

Targets

B-Raf: 24 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 92 mg/mL (178.45 mM); Water: Insoluble; Ethanol: 5 mg/mL (9.69 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

B-Raf IN 1 can be used to explore its inhibitory effects on BRAF in the context of cancer.

Storage

Store at -20ºC.