Raf inhibitor B-Raf inhibitor 1 dihydrochloride, Purity ≥98%

Synonym: 1191385-19-9; B-Raf inhibitor 1 dihydrochloride; 1,5-Isoquinolinediamine, N1-(4-chlorophenyl)-6-methyl-N5-[3-(9H-purin-6-yl)-2-pyridinyl]-, hydrochloride (1:2); HUN85199; Raf inhibitor 1 (dihydrochloride); B-Raf inhibitor 1 (dihydrochloride); 1-N-(4-chlorophenyl)-6-methyl-5-N-[3-(7H-purin-6-yl)pyridin-2-yl]isoquinoline-1,5-diamine; Raf inhibitor

CAS Number: 1191385-19-9
Compound CID: 44247765

Product Size

1 mg; 2 mg; 5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

B-Raf inhibitor 1 dihydrochloride, soluble in DMSO and insoluble in ethanol and water, blocks a MAPK/ERK signaling pathway. It targets B-Raf, B-Raf (V600E) and c-Raf.

Molecular Weight

551.86

Molecular Formula

C₂₆H₂₁Cl₃N₈

Targets

B-Raf: 1 nM; B-Raf (V600E): 1 nM; c-Raf: 0.3 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 96 mg/mL (173.95 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

B-Raf inhibitor 1 dihydrochloride can be utilized to investigate its selectivity and efficacy in inhibiting BRAF kinase.

Storage

Store at -20ºC.