Raf inhibitor B-Raf-inhibitor 1, Purity ≥98%

Synonym: B-Raf inhibitor 1; 1093100-40-3; Raf inhibitor 1; 1-N-(4-Chlorophenyl)-6-methyl-5-N-[3-(7H-purin-6-yl)pyridin-2-yl]isoquinoline-1,5-diamine; N1-(4-Chlorophenyl)-6-methyl-N5-[3-(9H-purin-6-yl)-2-pyridinyl]-1,5-isoquinolinediamine; Raf inhibitor

CAS Number: 1093100-40-3
Compound CID: 44223999

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

B-Raf-inhibitor 1 blocks a MAPK/ERK signaling pathway. It targets B-Raf, B-Raf (V600E), and c-Raf.

Molecular Weight

478.94

Molecular Formula

C₂₆H₁₉ClN₈

Targets

B-Raf: 1 nM (Ki); B-Raf (V600E): 1 nM (Ki); c-Raf: 1 nM (Ki)

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

B-Raf-inhibitor 1 can be used to study the oncogenic BRAF V600E inhibition in cancer research.

Storage

Store at -20ºC.