Raf inhibitor BI-882370, Purity ≥98%

Synonym: 1392429-79-6; BI-882370; BI 882370; XP 102; XP-102; V32TR55QP9; N-[3-[5-[(1-Ethylpiperidin-4-yl)-methylamino]-3-pyrimidin-5-ylpyrrolo[3,2-b]pyridin-1-yl]-2,4-difluorophenyl]propane-1-sulfonamide; Raf inhibitor

CAS Number: 1392429-79-6
Compound CID: 60152613

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

BI-882370 blocks a MAPK/ERK signaling pathway. It targets B-Raf, B-Raf (V600E) and c-Raf.

Molecular Weight

569.67

Molecular Formula

C₂₈H₃₃F₂N₇O₂S

Targets

B-Raf: 0.6 nM; B-Raf (V600E): 0.4 nM; c-Raf: 0.8 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

BI-882370 can be used for studying the inhibition of BRAF and CRAF kinases in oncology.

Storage

Store at -20ºC.