Raf inhibitor GDC-0879, Purity ≥98%

Synonym: GDC-0879; 905281-76-7; GDC0879; CHEBI:83405; AR-00341677; (E)-5-(1-(2-Hydroxyethyl)-3-(pyridin-4-yl)-1H-pyrazol-4-yl)-2,3-dihydroinden-1-one oxime; Raf inhibitor

CAS Number: 905281-76-7
Compound CID: 11717001

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GDC-0879, soluble in warmed DMSO and ethanol and insoluble in water, blocks a MAPK/ERK signaling pathway.

Molecular Weight

334.4

Molecular Formula

C₁₉H₁₈N₄O₂

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 65 mg/mL (194.39 mM); Water: Insoluble; Ethanol: 5 mg/mL (14.95 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

GDC-0879 can be applied to inhibit Raf kinases in the study of MAPK/ERK signaling pathways.

Storage

Store at -20ºC.