Raf inhibitor LGX 818, Purity ≥98%

Name: Raf inhibitor LGX 818, Purity ≥98%
SKU: X23-10-ZQ968

Synonym: Encorafenib; LGX818; 1269440-17-6; LGX-818; Braftovi; NVP-LGX818-NXA; Encorafenib (LGX818); Raf inhibitor

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

LGX 818, soluble in DMSO and ethanol and insoluble in water, blocks a MAPK/ERK signaling pathway. It targets BRAF V600E.

Molecular Weight

540.01

Molecular Formula

C₂₂H₂₇ClFN₇O₄S

Targets

BRAF V600E: 4 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 93 mg/mL (172.22 mM); Water: Insoluble; Ethanol: 93 mg/mL (172.22 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

LGX 818 can be used to inhibit BRAF and study its therapeutic effects on melanoma.