Cat. No.: X23-10-ZQ960
Raf inhibitor ML 786 dihydrochloride, Purity ≥98%
Synonym: ML 786 dihydrochloride; 1237536-18-3; MLN786 Dihydrochloride; ML786 (dihydrochloride); BGB659; 3-(1-Amino-1-methyl-ethyl)-N-[7-(7-oxo-5,6,7,8-tetrahydro-[1,8]naphthyridin-4-yloxy)-1,2,3,4-tetrahydro-naphthalen-2(R)-yl]-5-trifluoromethyl-benzamide dihydrochloride; Raf inhibitor
- CAS Number: 1237536-18-3
- Compound CID: 90488999
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
ML 786 dihydrochloride blocks a MAPK/ERK signaling pathway. It targets Abl1, DDR2, EPHA2, and KDR.
Molecular Formula
C29H29F3N4O3.2HCl
Targets
Abl1: <0.5 nM; DDR2: 7.0 nM; EPHA2: 11 nM; KDR: 6.2 nM
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
ML 786 dihydrochloride can be utilized to investigate the inhibition of specific protein kinases in cellular processes.
Related Products
