Cat. No.: X23-10-ZQ960
Raf inhibitor ML 786 dihydrochloride, Purity ≥98%
Synonym: ML 786 dihydrochloride; 1237536-18-3; MLN786 Dihydrochloride; ML786 (dihydrochloride); BGB659; 3-(1-Amino-1-methyl-ethyl)-N-[7-(7-oxo-5,6,7,8-tetrahydro-[1,8]naphthyridin-4-yloxy)-1,2,3,4-tetrahydro-naphthalen-2(R)-yl]-5-trifluoromethyl-benzamide dihydrochloride; Raf inhibitor
- CAS Number: 1237536-18-3
- Compound CID: 90488999
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
ML 786 dihydrochloride blocks a MAPK/ERK signaling pathway. It targets Abl1, DDR2, EPHA2, and KDR.
Molecular Formula
C29H29F3N4O3.2HCl
Targets
Abl1: <0.5 nM; DDR2: 7.0 nM; EPHA2: 11 nM; KDR: 6.2 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
ML 786 dihydrochloride can be utilized to investigate the inhibition of specific protein kinases in cellular processes.
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