Raf inhibitor PLX7904, Purity ≥98%

Synonym: PLX7904; 1393465-84-3; PB04; PLX-7904; N'-(3-{[5-(2-Cyclopropylpyrimidin-5-Yl)-1H-Pyrrolo[2,3-B]pyridin-3-Yl]carbonyl}-2,4-Difluorophenyl)-N-Ethyl-N-Methylsulfuric Diamide; PLX7904(PB04); 5-(2-Cyclopropylpyrimidin-5-yl)-3-[3-[[ethyl(methyl)sulfamoyl]amino]-2,6-difluorobenzoyl]-1H-pyrrolo[2,3-b]pyridine; Raf inhibitor

CAS Number: 1393465-84-3
Compound CID: 90116945

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

PLX7904, soluble in DMSO and insoluble in ethanol and water, blocks a MAPK/ERK signaling pathway.

Molecular Weight

512.53

Molecular Formula

C₂₄H₂₂F₂N₆O₃S

Form

Lyophilized powder

Purity

Solubility

DMSO: 87 mg/mL (169.75 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

PLX7904 can be utilized to study BRAF inhibition, particularly for research on resistant melanoma.