Raf inhibitor PLX7904, Purity ≥98%

Synonym: PLX7904; 1393465-84-3; PB04; PLX-7904; N'-(3-{[5-(2-Cyclopropylpyrimidin-5-Yl)-1H-Pyrrolo[2,3-B]pyridin-3-Yl]carbonyl}-2,4-Difluorophenyl)-N-Ethyl-N-Methylsulfuric Diamide; PLX7904(PB04); 5-(2-Cyclopropylpyrimidin-5-yl)-3-[3-[[ethyl(methyl)sulfamoyl]amino]-2,6-difluorobenzoyl]-1H-pyrrolo[2,3-b]pyridine; Raf inhibitor

CAS Number: 1393465-84-3
Compound CID: 90116945

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PLX7904, soluble in DMSO and insoluble in ethanol and water, blocks a MAPK/ERK signaling pathway.

Molecular Weight

512.53

Molecular Formula

C₂₄H₂₂F₂N₆O₃S

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 87 mg/mL (169.75 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

PLX7904 can be utilized to study BRAF inhibition, particularly for research on resistant melanoma.

Storage

Store at -20ºC.