Raf inhibitor RAF709, Purity ≥98%

Synonym: RAF709; 1628838-42-5; RAF-709; N-[6-Methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)pyridin-3-yl]pyridin-3-yl]-3-(trifluoromethyl)benzamide; N-(2-Methyl-5'-morpholino-6'-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3'-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide; N-{2-Methyl-5'-(Morpholin-4-Yl)-6'-[(Oxan-4-Yl)oxy][3,3'-Bipyridin]-5-Yl}-3-(Trifluoromethyl)benzamide; Raf inhibitor

CAS Number: 1628838-42-5
Compound CID: 90408826

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

RAF709, soluble in DMSO and ethanol and insoluble in water, blocks a MAPK/ERK signaling pathway. It targets B-Raf and CRAF.

Molecular Weight

542.55

Molecular Formula

C₂₈H₂₉F₃N₄O₄

Targets

B-Raf: 0.4 nM; CRAF: 0.5 nM

Form

Lyophilized powder

Purity

Solubility

DMSO: 86 mg/mL (158.51 mM); Water: Insoluble; Ethanol: 86 mg/mL (158.51 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

RAF709 can be applied in research studying selective inhibition of RAF kinases in cancer therapy.