Raf inhibitor RAF709, Purity ≥98%

Synonym: RAF709; 1628838-42-5; RAF-709; N-[6-Methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)pyridin-3-yl]pyridin-3-yl]-3-(trifluoromethyl)benzamide; N-(2-Methyl-5'-morpholino-6'-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3'-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide; N-{2-Methyl-5'-(Morpholin-4-Yl)-6'-[(Oxan-4-Yl)oxy][3,3'-Bipyridin]-5-Yl}-3-(Trifluoromethyl)benzamide; Raf inhibitor

CAS Number: 1628838-42-5
Compound CID: 90408826

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

RAF709, soluble in DMSO and ethanol and insoluble in water, blocks a MAPK/ERK signaling pathway. It targets B-Raf and CRAF.

Molecular Weight

542.55

Molecular Formula

C₂₈H₂₉F₃N₄O₄

Targets

B-Raf: 0.4 nM; CRAF: 0.5 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 86 mg/mL (158.51 mM); Water: Insoluble; Ethanol: 86 mg/mL (158.51 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

RAF709 can be applied in research studying selective inhibition of RAF kinases in cancer therapy.

Storage

Store at -20ºC.