Raf inhibitor SB590885, Purity ≥98%

Synonym: SB590885; 405554-55-4; SB-590885; 5-(2-(4-(2-(Dimethylamino)ethoxy)phenyl)-5-(pyridin-4-yl)-1H-imidazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime; SB 590885; (E)-5-(2-(4-(2-(Dimethylamino)ethoxy)phenyl)-5-(pyridin-4-yl)-1H-imidazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime; Raf inhibitor

CAS Number: 405554-55-4
Compound CID: 135421339

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SB590885, soluble in DMSO and insoluble in ethanol and water, blocks a MAPK/ERK signaling pathway. It targets B-Raf.

Molecular Weight

453.5

Molecular Formula

C₂₇H₂₇N₅O₂

Targets

B-Raf: 0.16 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 5 mg/mL (11.02 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

SB590885 can be used to study selective inhibition of BRAF kinase in cancer research.

Storage

Store at -20ºC.