Raf inhibitor SB590885, Purity ≥98%

Synonym: SB590885; 405554-55-4; SB-590885; 5-(2-(4-(2-(Dimethylamino)ethoxy)phenyl)-5-(pyridin-4-yl)-1H-imidazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime; SB 590885; (E)-5-(2-(4-(2-(Dimethylamino)ethoxy)phenyl)-5-(pyridin-4-yl)-1H-imidazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime; Raf inhibitor

CAS Number: 405554-55-4
Compound CID: 135421339

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SB590885, soluble in DMSO and insoluble in ethanol and water, blocks a MAPK/ERK signaling pathway. It targets B-Raf.

Molecular Weight

453.5

Molecular Formula

C₂₇H₂₇N₅O₂

Targets

B-Raf: 0.16 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 5 mg/mL (11.02 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

SB590885 can be used to study selective inhibition of BRAF kinase in cancer research.