Raf inhibitor TAK-632, Purity ≥98%

Synonym: TAK-632; 1228591-30-7; TAK632; N-(7-Cyano-6-(4-fluoro-3-(2-(3-(trifluoromethyl)phenyl)acetamido)phenoxy)benzo[d]thiazol-2-yl)cyclopropanecarboxamide; N-{7-Cyano-6-[4-fluoro-3-({[3-(Trifluoromethyl)phenyl]acetyl}amino)phenoxy]-1,3-Benzothiazol-2-Yl}cyclopropanecarboxamide; Raf inhibitor

MDL: MFCD26960965
CAS Number: 1228591-30-7
Compound CID: 46209401

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

TAK-632, soluble in DMSO and ethanol and insoluble in water, blocks a MAPK/ERK signaling pathway. It targets Aurora B, B-Raf, c-Kit, and c-Met.

Molecular Weight

554.51

Molecular Formula

C₂₇H₁₈F₄N₄O₃S

Targets

Aurora B: 66 nM; B-Raf: 8.3 nM; c-Kit: >10 μM; c-Met: >10 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 99 mg/mL (178.53 mM); Water: Insoluble; Ethanol: 2 mg/mL (3.6 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

TAK-632 can be applied to investigate pan-RAF inhibition in various cancer research models.

Storage

Store at -20ºC.