Properties
Description
6H05, soluble in DMSO, water and ethanol, blocks the activity of Ras proteins, which play a key role in cell signal transduction and are frequently implicated in oncogenic mutations.
Molecular Formula
C20H30ClN3O2S3
Solubility
DMSO: 93 mg/mL (157.59 mM); Water: 93 mg/mL (157.59 mM); Ethanol: 93 mg/mL (157.59 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
6H05 can be used to inhibit the interaction of Ras with its effectors; specifically targeting the SOS1-KRAS interaction.
