Properties
Description
6H05, soluble in DMSO, water and ethanol, blocks the activity of Ras proteins, which play a key role in cell signal transduction and are frequently implicated in oncogenic mutations.
Molecular Formula
C20H30ClN3O2S3
Solubility
DMSO: 93 mg/mL (157.59 mM); Water: 93 mg/mL (157.59 mM); Ethanol: 93 mg/mL (157.59 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
6H05 can be used to inhibit the interaction of Ras with its effectors; specifically targeting the SOS1-KRAS interaction.
