Properties
Description
AMG-510, soluble in DMSO and ethanol and insoluble in water, blocks the activity of Ras proteins, which play a key role in cell signal transduction and are frequently implicated in oncogenic mutations.
Molecular Formula
C30H30F2N6O3
Solubility
DMSO: 90 mg/mL (160.54 mM); Water: Insoluble; Ethanol: 90 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
AMG-510 can be used to target and inhibit KRAS G12C mutation in cancer studies.
