Ras inhibitor ARS-853, Purity ≥98%

Synonym: 1629268-00-3; ARS853; ARS 853; Ras inhibitor

CAS Number: 1629268-00-3
Compound CID: 86279165

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

ARS-853, soluble in warmed DMSO and warmed ethanol and insoluble in water, blocks the activity of Ras proteins, which play a key role in cell signal transduction and are frequently implicated in oncogenic mutations. It targets KRAS(G12C).

Molecular Weight

432.94

Molecular Formula

C₂₂H₂₉ClN₄O₃

Targets

KRAS(G12C): 2.5 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 80 mg/mL (184.78 mM); Water: Insoluble; Warmed ethanol: 1 mg/mL (2.3 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

ARS-853 can be used to study selective inhibition of KRAS G12C for targeted cancer therapy.

Storage

Store at -20ºC.