Properties
Description
EHop-016, soluble in DMSO and insoluble in ethanol and water, blocks the activity of Ras proteins, which play a key role in cell signal transduction and are frequently implicated in oncogenic mutations. It targets Rac1 (MDA-MB-435, MDA-MB-231 cells).
Molecular Formula
C25H30N6O
Targets
Rac1 (MDA-MB-435, MDA-MB-231 cells): 1.1 μM
Solubility
DMSO: 83 mg/mL (192.77 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
EHop-016 can be used to research inhibition of Rac1 in cancer metastasis.
