Properties
Description
Kobe0065, soluble in DMSO and ethanol and insoluble in water, blocks the activity of Ras proteins, which play a key role in cell signal transduction and are frequently implicated in oncogenic mutations.
Molecular Formula
C15H11ClF3N5O4S
Solubility
DMSO: 85 mg/mL (188.98 mM); Water: Insoluble; Ethanol: 12 mg/mL (26.68 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Kobe0065 can be employed in investigating Ras signaling inhibition.