Properties
Description
Kobe2602, soluble in DMSO and ethanol and insoluble in water, blocks the activity of Ras proteins, which play a key role in cell signal transduction and are frequently implicated in oncogenic mutations.
Molecular Formula
C14H9F4N5O4S
Solubility
DMSO: 79 mg/mL (188.4 mM); Water: Insoluble; Ethanol: 38 mg/mL (90.62 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Kobe2602 can be used to study inhibition of Ras signaling pathways in oncology.