Properties
Description
Kobe2602, soluble in DMSO and ethanol and insoluble in water, blocks the activity of Ras proteins, which play a key role in cell signal transduction and are frequently implicated in oncogenic mutations.
Molecular Formula
C14H9F4N5O4S
Solubility
DMSO: 79 mg/mL (188.4 mM); Water: Insoluble; Ethanol: 38 mg/mL (90.62 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Kobe2602 can be used to study inhibition of Ras signaling pathways in oncology.