Properties
Description
MRTX1257, soluble in DMSO and ethanol and insoluble in water, blocks the activity of Ras proteins, which play a key role in cell signal transduction and are frequently implicated in oncogenic mutations.
Molecular Formula
C33H39N7O2
Solubility
DMSO: 89 mg/mL (157.32 mM); Water: Insoluble; Ethanol: 27 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
MRTX1257 can be used to target KRAS G12C mutant cancers.
