Properties
Description
MRTX849, soluble in DMSO and ethanol and insoluble in water, blocks the activity of Ras proteins, which play a key role in cell signal transduction and are frequently implicated in oncogenic mutations.
Molecular Formula
C32H35ClFN7O2
Solubility
DMSO: 87 mg/mL (144.01 mM); Water: Insoluble; Ethanol: 44 mg/mL (72.83 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
MRTX849 can be used to target and inhibit mutant KRAS G12C in cancer therapy research.
