Properties
Description
MRTX849, soluble in DMSO and ethanol and insoluble in water, blocks the activity of Ras proteins, which play a key role in cell signal transduction and are frequently implicated in oncogenic mutations.
Molecular Formula
C32H35ClFN7O2
Solubility
DMSO: 87 mg/mL (144.01 mM); Water: Insoluble; Ethanol: 44 mg/mL (72.83 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
MRTX849 can be used to target and inhibit mutant KRAS G12C in cancer therapy research.
