Properties
Description
NSC 23766, soluble in warmed DMSO and warmed water and insoluble in ethanol, blocks the activity of Ras proteins, which play a key role in cell signal transduction and are frequently implicated in oncogenic mutations.
Molecular Formula
C24H35N7
Solubility
Warmed DMSO: 92 mg/mL (173.26 mM); Warmed water: 92 mg/mL (173.26 mM); Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
NSC 23766 can be used to study inhibition of Rac1 GTPase in cellular migration and cancer.