Properties
Description
NSC 23766, soluble in warmed DMSO and warmed water and insoluble in ethanol, blocks the activity of Ras proteins, which play a key role in cell signal transduction and are frequently implicated in oncogenic mutations.
Molecular Formula
C24H35N7
Solubility
Warmed DMSO: 92 mg/mL (173.26 mM); Warmed water: 92 mg/mL (173.26 mM); Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
NSC 23766 can be used to study inhibition of Rac1 GTPase in cellular migration and cancer.