Properties
Description
RBC8, soluble in DMSO and insoluble in ethanol and water, blocks the activity of Ras proteins, which play a key role in cell signal transduction and are frequently implicated in oncogenic mutations.
Molecular Formula
C25H20N4O3
Solubility
DMSO: 79 mg/mL (186.12 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
RBC8 can be used as an inhibitor of KRAS-driven cellular proliferation.