Ras inhibitor ZCL-278, Purity ≥98%

Synonym: 587841-73-4; ZCL278; ZCL 278; Ras inhibitor

CAS Number: 587841-73-4
Compound CID: 1791111

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

ZCL-278, soluble in DMSO and insoluble in ethanol and water, blocks the activity of Ras proteins, which play a key role in cell signal transduction and are frequently implicated in oncogenic mutations. It targets Cdc42 GTPase.

Molecular Weight

584.89

Molecular Formula

C₂₁H₁₉BrClN₅O₄S₂

Targets

Cdc42 GTPase: 11.4 μM(Kd)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 99 mg/mL (169.26 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

ZCL-278 can be used to study inhibition of Cdc42, a Rho GTPase, in cellular signaling.

Storage

Store at -20ºC.