Renin-angiotensin-aldosterone system (RAAS) inhibitor, GW4064, Purity ≥98%

Synonym: 278779-30-9; GW-4064; GW 4064; 3-[(E)-2-[2-Chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]ethenyl]benzoic acid; Renin-angiotensin-aldosterone system (RAAS) inhibitor

MDL: MFCD09971006
CAS Number: 278779-30-9
Compound CID: 9893571

Product Size

10 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GW4064, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting FXR. The molecular weight of the compound is 542.8, and its molecular formula is C₂₈H₂₂Cl₃NO₄. It targets the FXR (CV1).

Molecular Weight

542.8

Molecular Formula

C₂₈H₂₂Cl₃NO₄

Targets

FXR (CV1)

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 99 mg/mL (182.37 mM); Water: insoluble; Ethanol: insoluble; In vivo: 0.5% methylcellulose, 10 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

GW4064 can be studied extensively for its potential therapeutic applications in the treatment of liver diseases such as non-alcoholic fatty liver disease (NAFLD) and cholestasis.