Renin-angiotensin-aldosterone system (RAAS) inhibitor, Nidufexor, Purity ≥98%

Synonym: 1773489-72-7; LMB-763; LMB763; 4-[[Benzyl-(8-chloro-1-methyl-4H-chromeno[4,3-c]pyrazole-3-carbonyl)amino]methyl]benzoic acid; Renin-angiotensin-aldosterone system (RAAS) inhibitor

MDL: MFCD31657267
CAS Number: 1773489-72-7
Compound CID: 118063735

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Nidufexor, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting FXR. The molecular weight of the compound is 487.93, and its molecular formula is C₂₇H₂₂ClN₃O₄.

Molecular Weight

487.93

Molecular Formula

C₂₇H₂₂ClN₃O₄

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 96 mg/mL (196.74 mM); Water: insoluble; Ethanol: insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Nidufexor can be used for its ability to regulate bile acid and lipid metabolism, which can improve liver function and reduce fat accumulation in the liver.