Properties
Description
WAY-362450, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting FXR. The molecular weight of the compound is 438.47, and its molecular formula is C25H24F2N2O3. It targets the FXR.
Molecular Formula
C25H24F2N2O3
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO (warmed): 31 mg/mL (70.7 mM); Water: insoluble; Ethanol: 2 mg/mL (4.56 mM); In vivo: NMP + PEG300 (10 + 90, v + v) 28 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
WAY-362450 plays a key role in the regulation of bile acids and cholesterol levels, promoting hepatic lipid metabolism and reducing liver inflammation.