Reverse transcriptase inhibitor Dapivirine, Purity ≥98%

Synonym: 244767-67-7; Reverse transcriptase inhibitor; R 147681; TMC 120; TMC 120R147681

MDL: MFCD09833899
CAS Number: 244767-67-7
Compound CID: 214347

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Dapivirine, soluble in DMSO and insoluble in ethanol and water, obstructs the action of reverse transcriptase, an enzyme crucial for the replication of retroviruses like HIV. It targets HIV reverse transcriptase.

Molecular Weight

329.4

Molecular Formula

C₂₀H₁₉N₅

Targets

HIV reverse transcriptase: 24 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 29 mg/mL (88.03 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Dapivirine is utilized to examine its efficacy as a non-nucleoside reverse transcriptase inhibitor in HIV prevention.