Properties
Description
Entecavir hydrate, soluble in DMSO and insoluble in ethanol and water, obstructs the action of reverse transcriptase, an enzyme crucial for the replication of retroviruses like HIV. It targets reverse transcriptase.
Molecular Formula
C12H15N5O3.H2O
Targets
Reverse transcriptase
Solubility
DMSO: 52 mg/mL (176.09 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Entecavir hydrate is used in research for its inhibition of HBV DNA polymerase, aiding in hepatitis B studies.