Properties
Description
Riociguat (BAY 63-2521), soluble in DMSO and insoluble in water and ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets guanylate cyclase.
Molecular Formula
C20H19FN8O2
Targets
Guanylate cyclase
Solubility
DMSO: 76 mg/mL (179.91 mM); Water: insoluble; Ethanol: insoluble
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Riociguat (BAY 63-2521) can be used to increase levels of cyclic guanosine monophosphate (cGMP), leading to vasodilation and improved blood flow in the lungs.
Storage
Store at -20°C, and keep desiccated.
