RIP kinase inhibitor GSK481, Purity ≥98%

Synonym: 1622849-58-4; GSK481; GSK'481; GSK-481; (S)-5-Benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)isoxazole-3-carboxamide; RIP kinase inhibitor

CAS Number: 1622849-58-4
Compound CID: 90351311

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GSK481, soluble in DMSO and insoluble in ethanol and water, is a compound that targets RIP kinases and is a critical regulator of various cellular processes, including apoptosis, necroptosis, and inflammation. It targets RIP1.

Molecular Weight

377.39

Molecular Formula

C₂₁H₁₉N₃O₄

Targets

RIP1

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 70 mg/mL (185.48 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

GSK481 can be studied to understand its role in modulating RIP kinase-mediated pathways.

Storage

Store at -20ºC.