RIP kinase inhibitor GSK547, Purity ≥98%

Synonym: 2226735-55-1; GSK547; GSK'547; GSK-547; (S)-6-(4-(5-(3,5-Difluorophenyl)-4,5-dihydro-1H-pyrazole-1-carbonyl)piperidin-1-yl)pyrimidine-4-carbonitrile; 6-[4-[(3S)-3-(3,5-Difluorophenyl)-3,4-dihydropyrazole-2-carbonyl]piperidin-1-yl]pyrimidine-4-carbonitrile; RIP kinase inhibitor

CAS Number: 2226735-55-1
Compound CID: 134521814

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GSK547, soluble in DMSO and insoluble in ethanol and water, is a compound that targets RIP kinases and is a critical regulator of various cellular processes, including apoptosis, necroptosis, and inflammation.

Molecular Weight

396.39

Molecular Formula

C₂₀H₁₈F₂N₆O

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 26 mg/mL (65.59 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

GSK547 can be employed to investigate its role in modulating RIPK pathway signaling.

Storage

Store at -20ºC.