RIP kinase inhibitor GSK547, Purity ≥98%

Synonym: 2226735-55-1; GSK547; GSK'547; GSK-547; (S)-6-(4-(5-(3,5-Difluorophenyl)-4,5-dihydro-1H-pyrazole-1-carbonyl)piperidin-1-yl)pyrimidine-4-carbonitrile; 6-[4-[(3S)-3-(3,5-Difluorophenyl)-3,4-dihydropyrazole-2-carbonyl]piperidin-1-yl]pyrimidine-4-carbonitrile; RIP kinase inhibitor

CAS Number: 2226735-55-1
Compound CID: 134521814

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GSK547, soluble in DMSO and insoluble in ethanol and water, is a compound that targets RIP kinases and is a critical regulator of various cellular processes, including apoptosis, necroptosis, and inflammation.

Molecular Weight

396.39

Molecular Formula

C₂₀H₁₈F₂N₆O

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 26 mg/mL (65.59 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

GSK547 can be employed to investigate its role in modulating RIPK pathway signaling.