RIP kinase inhibitor GSK583, Purity ≥98%

Synonym: 1346547-00-9; GSK583; GSK 583; 6-(tert-Butylsulfonyl)-N-(5-fluoro-2H-indazol-3-Yl)quinolin-4-Amine; 6-(tert-Butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine; 6-tert-Butylsulfonyl-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine; RIP kinase inhibitor

MDL: MFCD30343846
CAS Number: 1346547-00-9
Compound CID: 67469084

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GSK583, soluble in DMSO and ethanol and insoluble in water, is a compound that targets RIP kinases and is a critical regulator of various cellular processes, including apoptosis, necroptosis, and inflammation.

Molecular Weight

398.45

Molecular Formula

C₂₀H₁₉FN₄O₂S

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 72 mg/mL (180.69 mM); Water: Insoluble; Ethanol: 25 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

GSK583 can be used to investigate the inhibition of RIPK2 and its potential therapeutic applications.

Storage

Store at -20ºC.