RIP kinase inhibitor GSK583, Purity ≥98%

Synonym: 1346547-00-9; GSK583; GSK 583; 6-(tert-Butylsulfonyl)-N-(5-fluoro-2H-indazol-3-Yl)quinolin-4-Amine; 6-(tert-Butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine; 6-tert-Butylsulfonyl-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine; RIP kinase inhibitor

MDL: MFCD30343846
CAS Number: 1346547-00-9
Compound CID: 67469084

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GSK583, soluble in DMSO and ethanol and insoluble in water, is a compound that targets RIP kinases and is a critical regulator of various cellular processes, including apoptosis, necroptosis, and inflammation.

Molecular Weight

398.45

Molecular Formula

C₂₀H₁₉FN₄O₂S

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 72 mg/mL (180.69 mM); Water: Insoluble; Ethanol: 25 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

GSK583 can be used to investigate the inhibition of RIPK2 and its potential therapeutic applications.