RIP kinase inhibitor GSK963, Purity ≥98%

Synonym: 2049868-46-2; GSK963; GSK-963; GSK'963; (S)-2,2-Dimethyl-1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)propan-1-one; RIP kinase inhibitor

CAS Number: 2049868-46-2
Compound CID: 122703613

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GSK963, soluble in DMSO and ethanol and insoluble in water, is a compound that targets RIP kinases and is a critical regulator of various cellular processes, including apoptosis, necroptosis, and inflammation.

Molecular Weight

230.311

Molecular Formula

C₁₄H₁₈N₂O

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 41 mg/mL (178.02 mM); Water: Insoluble; Ethanol: 41 mg/mL (178.02 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

GSK963 can be used to investigate RIPK1 inhibition and its implications in inflammation and cell death.