Properties
Description
Ripasudil, soluble in DMSO, ethanol and water, selectively inhibits the phosphorylation activity of ROCK, which is involved in various cellular processes. It targets ROCK1, and ROCK2.
Molecular Formula
C15H23ClFN3O4S
Targets
ROCK1: 51 nM; ROCK2: 19 nM
Solubility
DMSO: 25 mg/mL (63.14 mM); Water: 76 mg/mL (191.97 mM); Ethanol: 5 mg/mL (12.63 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Ripasudil can be used in the study of corneal endothelial dysfunction, a condition characterized by a decrease in the number or function of endothelial cells in the cornea.
Storage
Store at -20℃, and keep desiccated.
