Ripasudil

Synonym: 887375-67-9; Ripasudil hydrochloride dihydrate; Glanatec

CAS Number: 887375-67-9
PubChem CID: 11625386

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Ripasudil, soluble in DMSO, ethanol and water, selectively inhibits the phosphorylation activity of ROCK, which is involved in various cellular processes. It targets ROCK1, and ROCK2.

Molecular Weight

395.88

Molecular Formula

C₁₅H₂₃ClFN₃O₄S

Targets

ROCK1: 51 nM; ROCK2: 19 nM

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 25 mg/mL (63.14 mM); Water: 76 mg/mL (191.97 mM); Ethanol: 5 mg/mL (12.63 mM)

Applications

Ripasudil can be used in the study of corneal endothelial dysfunction, a condition characterized by a decrease in the number or function of endothelial cells in the cornea.