Cat. No.: X24-08-YM130
RNA-DNA polymerase inhibitor, Actinomycin D, Purity ≥98%
Synonym: 50-76-0; Actinomycin-D; 2-Amino-4,6-dimethyl-3-oxo-1-N,9-N-bis[(3R,6S,7R,10S,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide
- MDL: MFCD00005033
- CAS Number: 50-76-0
- Compound CID: 457193
Product Size
10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
Actinomycin D, soluble in DMSO and insoluble in water and ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting RNA-DNA polymerase.
Molecular Formula
C62H86N12O16
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 91 mg/mL (72.48 mM); Water: insoluble; Ethanol: insoluble
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
Actinomycin D is a DNA damage inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of Wilms’ tumor, rhabdomyosarcoma, and certain types of leukemia.
Storage
Store at -20ºC, and keep desiccated.
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