Properties
Description
Tenofovir, soluble in warmed DMSO and water and insoluble in ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting RNA-DNA polymerase.
Molecular Formula
C9H14N5O4P
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO (warmed): 4 mg/mL (13.92 mM); Water: 2 mg/mL (6.96 mM); Ethanol: insoluble; In vivo: 30% propylene glycol, 5% Tween 80, 65% D5W, 28 mg/mL
Applications
Tenofovir is a DNA damage inhibitor that plays a key role in blocking the reverse transcriptase enzyme, which is essential for the replication of HIV and HBV.