Properties
Description
RO4929097, soluble in DMSO and ethanol and insoluble in water, inhibits the activity of proteases, which are enzymes involved in the breakdown of proteins. It targets γ secretase (cell-free assay), γ secretase(ICN) (cell-free assay), and Aβ40 (cell-free assay).
Molecular Formula
C22H20F5N3O3
Targets
γ Secretase (Cell-free assay): 4 nM; γ Secretase (ICN) (Cell-free assay): 5 nM; Aβ40 (Cell-free assay): 14 nM
Solubility
DMSO: 92 mg/mL (195.99 mM); Water: insoluble; Ethanol: 16 mg/mL
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
RO4929097 can be studied in hematological malignancies, such as leukemia and lymphoma.
Storage
Store at -20℃, and keep desiccated.
