RO4929097

Synonym: 847925-91-1; RG-4733

CAS Number: 847925-91-1
PubChem CID: 49867930

Product Size

5 mg; 10 mg; 50 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

RO4929097, soluble in DMSO and ethanol and insoluble in water, inhibits the activity of proteases, which are enzymes involved in the breakdown of proteins. It targets γ secretase (cell-free assay), γ secretase(ICN) (cell-free assay), and Aβ40 (cell-free assay).

Molecular Weight

469.4

Molecular Formula

C₂₂H₂₀F₅N₃O₃

Targets

γ Secretase (Cell-free assay): 4 nM; γ Secretase (ICN) (Cell-free assay): 5 nM; Aβ40 (Cell-free assay): 14 nM

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 92 mg/mL (195.99 mM); Water: insoluble; Ethanol: 16 mg/mL

Applications

RO4929097 can be studied in hematological malignancies, such as leukemia and lymphoma.