Properties
Description
Roburic acid, a tetracyclic triterpenoid, is an inhibitor of COX with IC50 of 5μM and 9μM for COX-1 and COX-2, respectively.
Molecular Formula
C30H48O2
Source
The roots of Gentiana macrophylla Pall
Form
Clusters of white needles
Purity
>98%, determined by HPLC.
Solubility
It is insoluble in water, soluble in petroleum ether, n-hexane and ethyl acetate.
Identity
Confirmed by NMR and MS.
Applications
Roburic acid can be used for content determination, identification, and pharmacological experiments, etc.