Properties
Description
BDP5290 blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets MRCKα, MRCKβ, ROCK1, and ROCK2.
Molecular Formula
C17H18ClN7O
Targets
MRCKα: 10 nM; MRCKβ: 100 nM; ROCK1: 5 nM; ROCK2: 50 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
BDP5290 can be used to explore ROCK inhibition for therapeutic applications in neurological disorders.