Properties
Description
BDP5290 blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets MRCKα, MRCKβ, ROCK1, and ROCK2.
Molecular Formula
C17H18ClN7O
Targets
MRCKα: 10 nM; MRCKβ: 100 nM; ROCK1: 5 nM; ROCK2: 50 nM
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
BDP5290 can be used to explore ROCK inhibition for therapeutic applications in neurological disorders.