Properties
Description
Chroman 1 blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets MRCK, ROCK1, and ROCK2.
Molecular Formula
C24H28N4O4
Targets
MRCK: 150 nM; ROCK1: 52 pM; ROCK2: 1 pM
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Chroman 1 is used to investigate its role as a selective ROCK inhibitor in cell mobility and cytoskeletal organization.
